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Melatonin has been shown to have anti-inflammatory results, among a number of actions. Melatonin decreases tissue destruction during inflammatory reactions by a variety of ways. Hence melatonin, because of its ability to directly scavenge harmful totally free radicals, lowers macromolecular damage in all organs. The free radicals and reactive oxygen as well as nitrogen species known to be fed on by melatonin include the extremely hazardous hydroxyl radical, peroxynitrite anion, and also hypochlorous acid, among others. These agents all add to the inflammatory feedback as well as connected tissue damage. Furthermore, melatonin has various other means to lower the damages resulting from swelling.
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