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Melatonin has been shown to have anti-inflammatory results, among a number of actions. Melatonin minimizes tissue destruction throughout inflammatory reactions by a number of methods. Therefore melatonin, through its capability to directly scavenge harmful free radicals, minimizes macromolecular damages in all organs. The totally free radicals as well as responsive oxygen as well as nitrogen species understood to be scavenged by melatonin include the highly harmful hydroxyl radical, peroxynitrite anion, and hypochlorous acid, among others. These representatives all contribute to the inflammatory response and associated tissue damage. Additionally, melatonin has various other means to decrease the damage arising from swelling.
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