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Melatonin has been revealed to have anti-inflammatory impacts, amongst a number of actions. Melatonin reduces tissue damage during inflammatory responses by a variety of methods. Thus melatonin, because of its ability to directly feed on harmful free radicals, decreases macromolecular damage in all organs. The totally free radicals and reactive oxygen and nitrogen varieties recognized to be scavenged by melatonin include the very poisonous hydroxyl radical, peroxynitrite anion, as well as hypochlorous acid, among others. These agents all contribute to the inflammatory feedback and connected cells damage. Additionally, melatonin has other means to reduce the damage arising from swelling.
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