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Melatonin has actually been shown to have anti-inflammatory effects, among a variety of actions. Melatonin reduces cells devastation throughout inflammatory reactions by a number of means. Thus melatonin, through its capacity to directly feed on toxic free radicals, minimizes macromolecular damage in all organs. The totally free radicals and reactive oxygen and nitrogen species known to be scavenged by melatonin consist of the very hazardous hydroxyl radical, peroxynitrite anion, and also hypochlorous acid, among others. These agents all contribute to the inflammatory feedback and also associated tissue devastation. Additionally, melatonin has various other means to lower the damages arising from inflammation.
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